Run and hide

Nesiritide – Run and hide?

Data extraction: Data were extracted from FDA and sponsor documents and corroborated with published articles when available. Thirty-day survival was assessed by metaanalysis using a fixed-effects model and time-dependent risk by Kaplan-Meier analysis with Cox proportional hazards regression modeling. Where deaths were described within a range of days after treatment, an extreme assumption was m...

Hide and run

Arginine-based endoplasmic reticulum (ER)-localization signals are sorting motifs that are involved in the biosynthetic transport of multimeric membrane proteins. After their discovery in the invariant chain of the major histocompatibility complex class II, several hallmarks of these signals have emerged. They occur in polytopic membrane proteins that are subunits of membrane protein complexes;...

Run or Hide? Fixed and Moving Targets

We examine the time it takes for a random walk to hit an adversarial moving target. This problem was introduced by Aldous and Fill as the “cat and mouse” game. They conjectured that for every graph hitting an optimally moving target takes as long in expectation as hitting an optimally placed stationary target. We show this conjecture is false by presenting an instance of a graph where it takes ...

Relational Aggression and Burnout: Fight, Hide, or Run?

Activity Server: You can run but you can't hide

The activity server is a software utility that provides high-level information on what a user or a number of users are doing by combining data inputs from various sources. These sources are: 1) thejinger server, 2) the phone server, and 3) the location server. The finger server provides information on users' activities or lack thereof on hosts within a local network; the phone server abstracts ...